Table 4 Symptom severity based on the Memorial Symptoms Assessment Scale

Difficulty concentrating

75

1.9 (0.8)

1.0–4.0

25 (33.3)

37 (49.3)

11 (14.7)

2 (2.7)

Feeling nervous

97

2.0 (0.8)

1.0–4.0

17 (27.8)

45 (46.4)

23 (23.7)

2 (2.1)

Feeling sad

86

2.3 (0.9)

1.0–4.0

19 (22.1)

30 (34.9)

33 (38.4)

4 (4.7)

Worrying

103

2.1 (0.8)

1.0–4.0

29 (28.2)

42 (40.8)

29 (28.2)

3 (2.9)

“I don’t look like myself”

73

2.0 (1.0)

1.0–4.0

29 (39.7)

19 (26)

19 (26)

6 (8.2)

Lack of energy

207

2.5 (0.8)

1.0–4.0

17 (8.2)

83 (40.1)

90 (43.5)

17 (8.2)

Numbness/tingling in hands/feet

181

2.5 (0.8)

1.0–4.0

20 (11)

73 (40.3)

73 (40.3)

15 (8.3)

Dizziness

99

1.7 (0.7)

1.0–4.0

42 (42.4)

43 (43.4)

13 (13.1)

1 (1)

Pain

195

2.6 (0.8)

1.0–4.0

16 (8.2)

68 (34.9)

90 (46.2)

21 (10.8)

Difficulty sleeping

167

2.9 (0.8)

1.0–4.0

5 (3.0)

43 (25.7)

83 (49.7)

36 (21.6)

Dry mouth

90

2.1 (0.8)

1.0–4.0

20 (22.2)

45 (50)

21 (23.3)

4 (4.4)

Nausea

60

2.1 (0.8)

1.0–4.0

13 (21.7)

31 (51.7)

13 (21.7)

3 (5)

Vomiting

27

2.1 (0.8)

1.0–4.0

6 (22.2)

14 (51.9)

6 (22.2)

1 (3.7)

Change in the way food tastes

18

2.2 (1.2)

1.0–4.0

7 (38.9)

3 (16.7)

5 (27.8)

3 (16.7)

Lack of appetite

98

2.4 (0.7)

1.0–4.0

6 (6.1)

51 (52)

35 (35.7)

6 (6.1)

Weight loss

14

2.1 (1.0)

1.0–4.0

4 (28.6)

5 (35.7)

4 (28.6)

1 (7.1)

Difficulty swallowing

16

2.4 (1.0)

1.0–4.0

2 (12.5)

8 (50)

3 (18.8)

3 (18.8)

Cough

129

2.5 (0.9)

1.0–4.0

20 (15.5)

44 (34.1)

44 (34.1)

21 (16.3)

Shortness of breath

156

2.9 (0.7)

1.0–4.0

5 (3.2)

41 (26.3)

83 (53.2)

27 (17.3)

Swelling of arms/legs

82

2.3 (0.8)

1.0–4.0

12 (14.6)

39 (47.6)

27 (32.9)

4 (4.9)

Sweats

12

2.0 (0.9)

1.0–4.0

3 (25.0)

7 (58.3)

1 (8.3)

1 (8.3)

Itching

86

2.4 (0.8)

1.0–4.0

11 (12.8)

37 (43)

30 (34.9)

8 (9.3)

Mouth sores

8

2.6 (1.1)

1.0–4.0

1 (12.5)

3 (37.5)

2 (25)

2 (25)

Hair loss

44

2.5 (0.8)

1.0–4.0

4 (9.1)

19 (43.20)

17 (38.6)

4 (9.1)

Changes in skin

38

2.5 (0.8)

1.0–4.0

4 (10.5)

14 (36.8)

17 (44.7)

3 (7.9)

Feeling bloated

113

2.4 (0.8)

1.0–4.0

12 (10.6)

48 (42.5)

46 (40.7)

7 (6.2)

Problems with urination

79

2.6 (0.7)

1.0–4.0

6 (7.6)

27 (34.2)

41 (51.9)

5 (6.3)

Diarrhoea

14

2.2 (0.8)

1.0–3.0

3 (21.4)

5 (35.7)

6 (42.9)

0 (0.0)

Constipation

120

2.6 (0.7)

1.0–4.0

7 (5.8)

43 (35.8)

61 (50.8)

9 (7.5)

Problems with sexual interest or activity

23

3.0 (0.8)

2.0–4.0

0.00

6 (26.1)

10 (43.5)

7 (30.4)