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Table 2 Comparisons of the differences on the frequency, severity, and distress of symptoms within, among and between groups at baseline and post-intervention

From: A nurse versus a chatbot ‒ the effect of an empowerment program on chemotherapy-related side effects and the self-care behaviors of women living with breast Cancer: a randomized controlled trial

Outcomes

 

ChemoFreeBot

(n = 50)

mean (SD)

Routine care

(n = 50)

mean (SD)

Nurse – led education

(n = 50)

mean (SD)

F(p)

ChemoFreeBot

vs.

Routine care

ChemoFreeBot

vs.

Nurse-led education

Routine care

vs.

Nurse-led education

Symptom frequency

        

Physical

symptoms

Baseline

2.87 ± 0.32

2.83 ± 0.29

2.98 ± 0.31

147(p < .001*) a

   

Post-intervention

1.36 ± 0.28

2.78 ± 0.23

2.16 ± 0.53

76.075(p < .001*) b

p < .001 **

p < .001 **

p < .001**

    

147(p < .001*) c

   

Psychological

symptoms

Baseline

2.80 ± 0.38

2.76 ± 0.35

2.76 ± 0.34

443.192(p < .001*) a

   

Post-intervention

1.39 ± 0.40

2.00 ± 0.39

2.75 ± 0.30

63.198(p < .001*) b

p < .001 **

p < .001 **

p < .001 **

    

137.908(p < .001*) c

   

Total symptoms

Baseline

2.84 ± 0.33

2.89 ± 0.25

2.80 ± 0.26

778.765(p < .001*) a

   

Post-intervention

1.37 ± 0.30

2.10 ± 0.39

2.77 ± 0.21

97.0(p < .001*) b

p < .001 **

p < .001 **

p < .001 **

    

230.811(p < .001*) c

   

Symptom severity

        

Physical

symptoms

Baseline

2.87 ± 0.27

2.95 ± 0.23

2.83 ± 0.22

749.679(p < .001*) a

   

Post-intervention

1.43 ± 0.29

2.18 ± 0.47

2.80 ± 0.20

96.440(p < .001*) b

p < .001 **

p < .001 **

p < .001 **

    

220.462(p < .001*) c

   

Psychological

symptoms

Baseline

2.90 ± 0.32

2.84 ± 0.33

2.81 ± 0.36

451.251(p < .001*) a

   

Post-intervention

1.40 ± 0.43

2.06 ± 0.42

2.78 ± 0.33

62.137(p < .001*) b

p < .001 **

p < .001 **

p < .001 **

    

136.740(p < .001*) c

   

Total symptoms

Baseline

2.88 ± 0.26

2.91 ± 0.22

2.83 ± 0.22

835.079(p < .001*) a

   

Post-intervention

1.42 ± 0.30

2.14 ± 0.39

2.79 ± 0.21

111.596(p < .001*) b

p < .001 **

p < .001 **

p < .001 **

     

247.734(p < .001*) c

   

Symptom distress

        

Physical

symptoms

Baseline

2.89 ± 0.26

2.86 ± 0.29

2.97 ± 0.22

209.281(P < .001*) a

   

Post-intervention

1.85 ± 0.40

3.00 ± 0.32

2.76 ± 0.22

77.171(p < .001*) b

p < .001 **

p < .001 **

p = 1

    

189.680(p < .001*) c

   

Psychological

symptoms

Baseline

2.91 ± 0.37

2.96 ± 0.33

2.85 ± 0.34

106.564(p < .001*) a

   

Post-intervention

1.68 ± 0.71

2.75 ± 0.33

3.00 ± 0.34

43.003(p < .001*) b

p < .001 **

p < .001 **

p = 1

    

168.057(p < .001*) c

   

Total symptoms

Baseline

2.90 ± 0.27

2.93 ± 0.21

2.84 ± 0.26

219.276(p < .001*) a

   

Post-intervention

1.80 ± 0.43

2.78 ± 0.20

3.00 ± 0.30

80.265(p < .001*) b

p < .034 **

p < .001 **

p = .642

    

234.146(p < .001*) c

   
  1. F: Mixed design Repeated Measures ANOVA test, SD: Standard deviation, *: Statistically significant at p ≤ .05, ** Significant results after Adjustment for multiple comparisons: Bonferroni
  2. Mixed design repeated measures ANOVA test to assess main effect of time before and after intervention a, main effect of three programs b and interaction to assess the pattern of change of each quantitative outcome variable along time by program c.